On Saturday, October 1st the Buckeyes will open the month of October and play their 5th game of the season against the Michigan State Spartans. OSU has won the last 7 matchups in their long history with the most recent a 45-7 win in 2008.

Last 5 Historical Scores for Ohio State vs. Michigan State
| Year |
Score |
| 2008 |
W 45-7 |
| 2007 |
W 24-17 |
| 2006 |
W 38-7 |
| 2005 |
W 35-24 |
| 2004 |
W 32-19 |
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